Marla Dubinsky, MD

Director, Pediatric Inflammatory Bowel Disease Program
Email:marla.dubinsky@cshs.org
Phone:(310) 423-7100
Fax:(310) 423-1402

Institute Affiliation

Immunobiology Research Institute

Academic Appointments

Associate Professor, Pediatrics

Awards and Activities

Lenny and Corrine Sands Clinical Investigator Award2007
Crohn's and Colitis Foundation of America2001 - 2008
North American Society of Pediatric Gastroenterology, Hepatology and Nutrition2001 - 2008
American Gastroenterology Association2001 - 2008
American College of Gastroenterolgy2001 - 2008
Medical Advisory Chair, CCFA Los Angeles Chapter2004 - 2010
Chair, IBD Committee, NASPGHAN2005 - 2007

Research Focus

Genetic and immune translational research in the field of inflammatory bowel disease. The laboratory is studying the natural history of the disease and investigating predictors of disease course. The research uncovers predictors of rapid disease progression with the goal of preventing complications by altering treatment plans.

Research Contributions

Research contributions have pioneered novel approaches to predicting disease course in children which impact treatments and disease outcome.

Current investigations include:

Serological immune markers in inflammatory bowel disease. Genetic associations with immune pathways. Prognostic information. Clinical and translational research.

Selected Publications

  1. Dubinsky MC: Clinical perspectives in Crohn's disease. Serologic and prognostic biomarkers: who, when, and how?. Reviews in gastroenterological disorders, 7 Suppl 2: S3-7, 2007
  2. Dubinsky M: Special issues in pediatric inflammatory bowel disease. World J. Gastroenterol., 14(3): 413-20, 2008
  3. Dubinsky MC, Lin YC, Dutridge D, Picornell Y, Landers CJ, Farrior S, Wrobel I, Quiros A, Vasiliauskas EA, Grill B, Israel D, Bahar R, Christie D, Wahbeh G, Silber G, Dallazadeh S, Shah P, Thomas D, Kelts D, Hershberg RM, Elson CO, Targan SR, Taylor KD, Rotter JI, Yang H, : Serum immune responses predict rapid disease progression among children with Crohn's disease: immune responses predict disease progression. Am. J. Gastroenterol., 101(2): 360-7, 2006
  4. Dubinsky MC, Wang D, Picornell Y, Wrobel I, Katzir L, Quiros A, Dutridge D, Wahbeh G, Silber G, Bahar R, Mengesha E, Targan SR, Taylor KD, Rotter JI, : IL-23 receptor (IL-23R) gene protects against pediatric Crohn's disease. Inflamm. Bowel Dis., 13(5): 511-5, 2007